Traffic was backed up in the east-bound lane of I-20 in Tyler this afternoon after a crash killed two people and sent two others to the hospital. It happened shortly after 5:00 p.m. between mile markers 548 and 549. That's near FM 849. Officials say an 18-wheeler traveling west bound crossed the center lane and struck an SUV, which was going east-bound. DPS says there were three people in the SUV. One of them was transported to the hospital. The driver of the truck was transported to the hospital.